Our Publications : More Publications

More Publications

Shehadeh, L. A., Yu, K., Wang, L., Guevara, A., Singer, C., Vance, J., & Papapetropoulos, S. (2010). SRRM2, a potential blood biomarker revealing high alternative splicing in Parkinson’s disease. PloS one, 5(2), e9104.

Zheng, B., Liao, Z., Locascio, J. J., Lesniak, K. A., Roderick, S. S., Watt, M. L., … & Grünblatt, E. (2010). PGC-1α, a potential therapeutic target for early intervention in Parkinson’s disease. Science translational medicine,2(52), 52ra73-52ra73.

Bademci, G., Edwards, T. L., Torres, A. L., Scott, W. K., Züchner, S., Martin, E. R., … & Wang, L. (2010). A rare novel deletion of the tyrosine hydroxylase gene in Parkinson disease. Human mutation, 31(10), E1767-E1771.

Vance, J. M., Ali, S., Bradley, W. G., Singer, C., & Di Monte, D. A. (2010). Gene–environment interactions in Parkinson’s disease and other forms of parkinsonism. Neurotoxicology, 31(5), 598-602.

Alcalay, R. N., Caccappolo, E., Mejia-Santana, H., Tang, M. X., Rosado, L., Ross, B. M., … & Colcher, A. (2010). Frequency of known mutations in early-onset Parkinson disease: implication for genetic counseling: the consortium on risk for early onset Parkinson disease study. Archives of neurology, 67(9), 1116-1122.

Naj, A. C., Beecham, G. W., Martin, E. R., Gallins, P. J., Powell, E. H., Konidari, I., … & Vance, J. M. (2010). Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities. PLoS Genet, 6(9), e1001130.

Hamza, T. H., Zabetian, C. P., Tenesa, A., Laederach, A., Montimurro, J., Yearout, D., … & Kusel, V. I. (2010). Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson’s disease. Nature genetics, 42(9), 781-785.

Alcalay, R. N., Mejia-Santana, H., Tang, M. X., Rakitin, B., Rosado, L., Ross, B., … & Colcher, A. (2010). Self-report of cognitive impairment and mini-mental state examination performance in PRKN, LRRK2, and GBA carriers with early onset Parkinson’s disease. Journal of clinical and experimental neuropsychology, 32(7), 775-779.

Chung, C. Y., Licznerski, P., Alavian, K. N., Simeone, A., Lin, Z., Martin, E., … & Isacson, O. (2010). The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons. Brain, awq142.

Beecham, G. W., Naj, A., Gilbert, J. R., Haines, J. L., Buxbaum, J. D., & Pericak-Vance, M. A. (2010). PCDH11X variation is not associated with late-onset Alzheimer disease susceptibility. Psychiatric genetics, 20(6), 321.

Edwards, T. L., Scott, W. K., Almonte, C., Burt, A., Powell, E. H., Beecham, G. W., … & Singer, C. (2010). Genome‐wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. Annals of human genetics, 74(2), 97-109.

Marder, K. S., Tang, M. X., Mejia-Santana, H., Rosado, L., Louis, E. D., Comella, C. L., … & Bressman, S. (2010). Predictors of parkin mutations in early-onset Parkinson disease: the consortium on risk for early-onset Parkinson disease study. Archives of neurology, 67(6), 731-738.

Edwards, T. L., Scott, W. K., Almonte, C., Burt, A., Powell, E. H., Beecham, G. W., … & Singer, C. (2010). Genome‐wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. Annals of human genetics, 74(2), 97-109.

Shehadeh L, Martin E, Scott W, Yu K, Wang L, Burt A, Guevara A, Singer C, Vance J, and Papapetropoulos S. (2009). Finding Blood Biomarkers in Parkinson’s Disease using mRNA, miRNA, and SNP analysis. Nature Biotechnology Short Reports, v20, p57.

Gao, X., Martin, E. R., Liu, Y., Mayhew, G., Vance, J. M., & Scott, W. K. (2009). Genome-wide linkage screen in familial Parkinson disease identifies loci on chromosomes 3 and 18. The American Journal of Human Genetics,84(4), 499-504.

Hancock, D. B., Martin, E. R., Vance, J. M., & Scott, W. K. (2008). Nitric oxide synthase genes and their interactions with environmental factors in Parkinson’s disease. Neurogenetics, 9(4), 249-262.

Ewens, W. J., Spielman, R. S., Kaplan, N. L., Gao, X., Morris, R. W., & Martin, E. R. (2008). Disease Associations and Family‐Based Tests. Current Protocols in Human Genetics=, 1-12.

Chung, R. H., Morris, R. W., Zhang, L., Li, Y. J., & Martin, E. R. (2007). X-APL: an improved family-based test of association in the presence of linkage for the X chromosome. The American Journal of Human Genetics, 80(1), 59-68.

Zhang, L., Martin, E. R., Chung, R. H., Li, Y. J., & Morris, R. W. (2008).X‐LRT: a likelihood approach to estimate genetic risks and test association with X‐linked markers using a case‐parents design. Genetic epidemiology,32(4), 370-380.

Gao, X., Starmer, J., & Martin, E. R. (2008). A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms. Genetic epidemiology, 32(4), 361-369.

Wang, G., van der Walt, J. M., Mayhew, G., Li, Y. J., Züchner, S., Scott, W. K., … & Vance, J. M. (2008). Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of α-synuclein. The American Journal of Human Genetics, 82(2), 283-289.

Gao, X., Scott, W. K., Wang, G., Mayhew, G., Li, Y. J., Vance, J. M., & Martin, E. R. (2008). Gene‐Gene Interaction Between FGF20 and MAOB in Parkinson Disease. Annals of human genetics, 72(2), 157-162.

Hancock, D. B., Martin, E. R., Mayhew, G. M., Stajich, J. M., Jewett, R., Stacy, M. A., … & Scott, W. K. (2008). Pesticide exposure and risk of Parkinson’s disease: a family-based case-control study. BMC neurology,8(1), 6.

Lin, P. I., Vance, J. M., Pericak-Vance, M. A., & Martin, E. R. (2007). No gene is an island: the flip-flop phenomenon. The American Journal of Human Genetics, 80(3), 531-538.

Li, Y. J., Deng, J., Mayhew, G. M., Grimsley, J. W., Huo, X., & Vance, J. M. (2007). Investigation of the PARK10 gene in Parkinson disease. Annals of human genetics, 71(5), 639-647.

Hancock, D. B., Martin, E. R., Li, Y. J., & Scott, W. K. (2007). Methods for interaction analyses using family‐based case‐control data: conditional logistic regression versus generalized estimating equations. Genetic epidemiology, 31(8), 883-893.

Hancock, D. B., & Scott, W. K. (2012). Population‐Based Case‐Control Association Studies=. Current protocols in human genetics, 1-17.

Hancock, D. B., Martin, E. R., Stajich, J. M., Jewett, R., Stacy, M. A., Scott, B. L., … & Scott, W. K. (2007). Smoking, caffeine, and nonsteroidal anti-inflammatory drugs in families with Parkinson disease. Archives of neurology, 64(4), 576-580.

Clark, L. N., Haamer, E., Mejia‐Santana, H., Harris, J., Lesage, S., Durr, A., … & Andrews, H. (2007). Construction and validation of a Parkinson’s disease mutation genotyping array for the Parkin gene. Movement disorders, 22(7), 932-937.

Scherzer, C. R., Eklund, A. C., Morse, L. J., Liao, Z., Locascio, J. J., Fefer, D., … & Sudarsky, L. R. (2007). Molecular markers of early Parkinson’s disease based on gene expression in blood. Proceedings of the National Academy of Sciences, 104(3), 955-960.

Golbe, L. I., Iorio, G. D., Markopoulou, K., Athanassiadou, A., Papapetropoulos, S., Watts, R. L., … & Stenroos, E. S. (2007). Glutathione S‐transferase polymorphisms and onset age in α‐synuclein A53T mutant Parkinson’s disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 144(2), 254-258.

Hancock, D. B., Martin, E. R., Fujiwara, K., Stacy, M. A., Scott, B. L., Stajich, J. M., … & Scott, W. K. (2006). NOS2A and the modulating effect of cigarette smoking in Parkinson’s disease. Annals of neurology, 60(3), 366-373.

Li, Y. J., Scott, W. K., Zhang, L., Lin, P. I., Oliveira, S. A., Skelly, T., … & Pericak-Vance, M. A. (2006).Revealing the role of glutathione S-transferase omega in age-at-onset of Alzheimer and Parkinson diseases. Neurobiology of aging, 27(8), 1087-1093.

Kang, S. J., Scott, W. K., Li, Y. J., Hauser, M. A., van der Walt, J. M., Fujiwara, K., … & Martin, E. R. (2006).Family‐based case–control study of MAOA and MAOB polymorphisms in Parkinson disease. Movement disorders, 21(12), 2175-2180.

Noureddine, M. A., Li, Y. J., van der Walt, J. M., Walters, R., Jewett, R. M., Xu, H., … & Schmechel, D. (2005). Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra. Movement disorders, 20(10), 1299-1309.

Scott, W. K., Zhang, F., Stajich, J. M., Scott, B. L., Stacy, M. A., & Vance, J. M. (2005). Family-based case-control study of cigarette smoking and Parkinson disease. Neurology, 64(3), 442-447.

Oliveira, S. A., Li, Y. J., Noureddine, M. A., Züchner, S., Qin, X., Pericak-Vance, M. A., & Vance, J. M. (2005). Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease. The American Journal of Human Genetics, 77(2), 252-264.

Stenger, J. E., Xu, H., Haynes, C., Hauser, E. R., Pericak-Vance, M., Goldschmidt-Clermont, P. J., & Vance, J. M. (2005). Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser. BMC bioinformatics, 6(1), 95.

Noureddine, M. A., Qin, X. J., Oliveira, S. A., Skelly, T. J., van der Walt, J., Hauser, M. A., … & Li, Y. J. (2005). Association between the neuron-specific RNA-binding protein ELAVL4 and Parkinson disease. Human genetics,117(1), 27-33.

Hauser, M. A., Li, Y. J., Xu, H., Noureddine, M. A., Shao, Y. S., Gullans, S. R., … & Scott, B. L. (2005). Expression profiling of substantia nigra in Parkinson disease, progressive supranuclear palsy, and frontotemporal dementia with parkinsonism. Archives of neurology, 62(6), 917-921.

Oliveira, S. A., Scott, W. K., Zhang, F., Stajich, J. M., Fujiwara, K., Hauser, M., … & Martin, E. R. (2004).Linkage disequilibrium and haplotype tagging polymorphisms in the Tau H1 haplotype. Neurogenetics, 5(3), 147-155.

Saito, Y., Suzuki, K., Hulette, C. M., & Murayama, S. (2004). Aberrant phosphorylation of α-synuclein in human Niemann-Pick type C1 disease. Journal of Neuropathology & Experimental Neurology, 63(4), 323-328.

Van Der Walt, J. M., Noureddine, M. A., Kittappa, R., Hauser, M. A., Scott, W. K., McKay, R., … & Pericak-Vance, M. A. (2004). Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease. The American Journal of Human Genetics, 74(6), 1121-1127.

Li, Y. J., Hauser, M. A., Scott, W. K., Martin, E. R., Booze, M. W., Qin, X. J., … & Pahwa, R. (2004). Apolipoprotein E controls the risk and age at onset of Parkinson disease. Neurology, 62(11), 2005-2009.

Kawaguchi, Y., Kovacs, J. J., McLaurin, A., Vance, J. M., Ito, A., & Yao, T. P. (2003). The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Cell, 115(6), 727-738.

Li, Y. J., Oliveira, S. A., Xu, P., Martin, E. R., Stenger, J. E., Scherzer, C. R., … & Watts, R. L. (2003). Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease. Human molecular genetics, 12(24), 3259-3267.

Martin, E. R., Bass, M. P., Gilbert, J. R., Pericak‐Vance, M. A., & Hauser, E. R. (2003). Genotype‐based association test for general pedigrees: The genotype‐PDT. Genetic epidemiology, 25(3), 203-213.

Hulette, C. M. (2003). Brain banking in the United States. Journal of Neuropathology & Experimental Neurology, 62(7), 715-722.

Fessel, J. P., Hulette, C., Powell, S., Roberts, L. J., & Zhang, J. (2003). Isofurans, but not F2‐isoprostanes, are increased in the substantia nigra of patients with Parkinson’s disease and with dementia with Lewy body disease. Journal of neurochemistry, 85(3), 645-650.

Oliveira, S. A., Scott, W. K., Nance, M. A., Watts, R. L., Hubble, J. P., Koller, W. C., … & Jankovic, J. (2003). Association study of Parkin gene polymorphisms with idiopathic Parkinson disease. Archives of neurology, 60(7), 975-980.

Oliveira SA, Scott WK, Martin ER, Pericak-Vance MA, Vance JM. Frequency of Parkin mutations in late-onset Parkinson disease [reply]. (2003). Letter to the Editor, Annals of Neurology; 54:416-417.

Oliveira, S. A., Martin, E. R., Scott, W. K., Nicodemus, K. K., Small, G. W., Schmechel, D. E., … & Haines, J. L. (2003). The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease. Neuroscience letters, 347(3), 143-146.

Van der Walt, J. M., Martin, E. R., Scott, W. K., Zhang, F., Nance, M. A., Watts, R. L., … & Pahwa, R. (2003). Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson’s disease. Neurology, 60(7), 1189-1191.

Van Der Walt, J. M., Nicodemus, K. K., Martin, E. R., Scott, W. K., Nance, M. A., Watts, R. L., … & Pahwa, R. (2003).Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. The American Journal of Human Genetics, 72(4), 804-811.

Trembath, Y., Rosenberg, C., Ervin, J. F., Schmechel, D. E., Gaskell, P., Pericak-Vance, M., … & Hulette, C. M. (2003). Lewy body pathology is a frequent co-pathology in familial Alzheimer’s disease. Acta neuropathologica,105(5), 484-488.

Oliveira, S. A., Scott, W. K., Martin, E. R., Nance, M. A., Watts, R. L., Hubble, J. P., … & Ondo, W. G. (2003). Parkin mutations and susceptibility alleles in late‐onset Parkinson’s disease. Annals of neurology, 53(5), 624-629.

Hauser, M. A., Li, Y. J., Takeuchi, S., Walters, R., Noureddine, M., Maready, M., … & Xu, H. (2003). Genomic convergence: identifying candidate genes for Parkinson’s disease by combining serial analysis of gene expression and genetic linkage. Human molecular genetics, 12(6), 671-677.

Li, Y. J., Zhang, L., Speer, M. C., & Martin, E. R. (2002). Evaluation of current methods of testing differential gene expression and beyond. In Methods of Microarray Data Analysis II. 185-194). Springer US.

Pericak-Vance MA, Scott WK, Martin ER, Vance JM, Haines JL. (2002). Identifying genetic factors in Parkinson disease [reply]. Letter to the Editor,JAMA 287:715-716

Gu, G., Reyes, P. F., Golden, G. T., Woltjer, R. L., Hulette, C., Montine, T. J., & Zhang, J. (2002). Mitochondrial DNA deletions/rearrangements in parkinson disease and related neurodegenerative disorders. Journal of Neuropathology & Experimental Neurology, 61(7), 634-639.

Li, Y. J., Scott, W. K., Hedges, D. J., Zhang, F., Gaskell, P. C., Nance, M. A., … & Stern, M. B. (2002). Age at onset in two common neurodegenerative diseases is genetically controlled. The American Journal of Human Genetics, 70(4), 985-993.

Kaplan, N. L., & Martin, E. R. (2001). Power calculations for a general class of tests of linkage and association that use nuclear families with affected and unaffected sibs. Theoretical population biology, 60(3), 193-201.

Kaplan, N. L., Monks, S. A., & Martin, E. R. (2000). A test for linkage and association in general pedigrees. GeneScreen, 1(2), 65-67.

Oliveira, S. A., Scott, W. K., Pericak-Vance, M. A., & Vance, J. M. (2001). Dissecting a complex disease using modern techniques of molecular biology. Laboratory Medicine, 32(10), 594-598.

Martin, E. R., Scott, W. K., Nance, M. A., Watts, R. L., Hubble, J. P., Koller, W. C., … & Hiner, B. C. (2001). Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease. JAMA, 286(18), 2245-2250.

Martin ER, Bass MP, Kaplan NL. (2001). Correcting for a potential bias in the pedigree disequilibrium test. Am J Hum Genet 68:1065-1067

Martin, E. R., Monks, S. A., Warren, L. L., & Kaplan, N. L. (2000). A test for linkage and association in general pedigrees: the pedigree disequilibrium test. The American Journal of Human Genetics, 67(1), 146-154.